Interaction charts on this desk are for reading, not for writing a prescription or filling a bottle. Open the orbit disclaimer
Orbit · Orbit · CNS
Last reviewed · 14 min read · Updated
Orbit card
| Onset | Tone change over days of titration |
|---|---|
| Duration | t½ ~2-6 h; effect follows schedule |
| Food | With or without food |
| Alcohol | Additive CNS depression - avoid stack |
Orbit · baclofen 5 mg tablets. Withdrawal and stack reference from Laugavegur 28 - not a pump clinic.
Abrupt discontinuation - empty bottle, missed refill, 'I felt weak so I stopped' - has produced hallucinations, seizures, high fever, rebound rigidity, and rare multi-organ failure. Except for a serious adverse reaction, the dose comes down slowly.
The Caelum lock is generic baclofen 5 mg, ninety tablets, the low-step board. Ten- and twenty-milligram rows are other NDCs. Starting language is low and divided. The oral ceiling is 80 mg daily (20 mg four times a day) for typical adults.
If you already ran out, the taper trace is not the first click - a bridge supply is. Then read the trace.
Alcohol, opioids, benzodiazepines, and other relaxants add CNS depression. 'Light wine' is how people miss a step.
Tizanidine is a class alternative with a CYP1A2 wall. Switching can be right. Stopping baclofen the same afternoon you start Zanaflex is how two problems arrive at once. See tizanidine.
Methocarbamol is a short-spasm cousin, not a GABA-B twin. Do not treat them as interchangeable refills.
| Absorption | Oral uptake; food optional. |
|---|---|
| Distribution | CNS and spinal GABA-B effect is the point. |
| Metabolism | Limited hepatic drama compared with tizanidine's CYP1A2 story. |
| Excretion | Renal excretion; accumulation in CKD and many older adults. |
The spasm orbit keeps function scores. Weakness that steals walking is a reason to split differently or switch class, not a reason to vanish off the drug.
If benefits never appear after a fair trial, withdraw slowly. That sentence is on the label for a reason.
Personal milligram maps stay with the clinician who can see you this week.
Baclofen chips
The Caelum lock is generic baclofen 5 mg, ninety tablets. Ten-milligram sixties and twenty-milligram nineties are other rows. Do not stop cold. A coupon does not write a taper.
Caelum does not dispense.
Generic baclofen 5 mg x 90, GoodRx tablet table, 21 August 2026.
Generic baclofen 5 mg, ninety tablets, the Caelum low-step spasm orbit, August 2026. GoodRx lists 5 mg x 90 at $111.18 / $19.69. Ten-milligram sixties and twenty-milligram nineties are other rows. Do not stop cold. Caelum does not dispense.
Withdrawal can include hallucinations, seizures, high fever, rebound rigidity, and rare multi-organ failure. Early signs can look like more spasm, itch, or tingling. Treat a high-dose gap as urgent.
The oral ceiling is 80 mg daily for typical adults - 20 mg four times a day. CKD and many older adults need a lower ceiling. Confusion that looks psychiatric can be accumulation.
The 5 mg lock is a low-step board. Jumping to 20 mg TID on night one is how people decide baclofen 'only weakens.'
Intrathecal pumps are another labeled world. Oral leftover 5 mg tablets are not a travel patch without the pump clinic.
Alcohol, opioids, and benzodiazepines add CNS depression. Light wine is how stairs get missed.
Epilepsy is a caution - seizure control can worsen on baclofen, and withdrawal can seize on its own.
Tizanidine is a class look with a CYP1A2 wall. Switching can be right. Stopping baclofen the same afternoon you start Zanaflex is two problems at once.
Neonatal withdrawal is labeled when oral baclofen runs through late pregnancy. Obstetric plans are written.
| Gap story | Move |
|---|---|
| Empty Sunday at high total | Bridge today |
| CKD + 80 mg target | Recut ceiling |
| Pump + oral add | Call pump team |
| Wine + night dose | Skip drink |
Withdrawal can include hallucinations, seizures, high fever, rebound rigidity, and rare multi-organ failure. Early signs can look like more spasm, itch, or tingling. Treat a high-dose gap as urgent, not as a Sunday off.
The oral ceiling is 80 mg daily for typical adults - 20 mg four times a day. Forum 120 mg plans do not enter this chart. CKD and many older adults need a lower ceiling. Confusion that looks psychiatric can be accumulation.
The 5 mg lock is a low-step board. Jumping to 20 mg TID on night one is how people decide baclofen only weakens. Titration language is low and divided.
Intrathecal pumps are another labeled world. Oral leftover 5 mg tablets are not a travel patch or a ten-tablet night cover without the pump clinic. Alarms are specialist emergencies.
Alcohol, opioids, and benzodiazepines add CNS depression. Light wine is how stairs get missed even at 5 mg.
Epilepsy is a caution. Seizure control can worsen on baclofen, and withdrawal can seize on its own. Neurology should see the joined chart.
Tizanidine is a class look with a CYP1A2 wall. Switching can be right. Stopping baclofen the same afternoon you start Zanaflex is two problems at once.
Neonatal withdrawal is labeled when oral baclofen runs through late pregnancy. Do not cold-stop a mid-pregnancy total. Obstetrics and neurology write the map.
Walking distance can outrank a prettier spasm diary. GABA-B relief is also GABA-B weakness. Secret noon skips after a stable total can start withdrawal.
Not indicated for rheumatic muscle ache. Copying a sports 5 mg habit onto MS - or the reverse - scrambles expectations.
If benefits never appear after a fair trial, withdraw slowly. That sentence is on the label for a reason.
Methocarbamol is a short-spasm cousin, not a GABA-B twin. Casual leftover swaps inherit the wrong withdrawal story.
Repeat eGFR after hospital vomiting. A 'normal' total becomes encephalopathy when clearance falls. Your brother's 80 mg walk is not your clearance.
Peer-pass wants last dose time and pump status on the same slip. Ingrid does not taper by mail.
Sources stay DailyMed withdrawal, 80 mg ceiling, epilepsy and renal cautions. Seizure or high fever after a gap: 112. Reviewed 21 August 2026.
Epilepsy is a caution. Seizure control can worsen on baclofen. Withdrawal can seize on its own.
Tizanidine is a class look with a CYP1A2 wall. Do not cold-stop baclofen the afternoon Zanaflex starts.
Neonatal withdrawal is labeled when oral baclofen runs through late pregnancy. Obstetrics writes the map.
Walking distance can outrank a prettier spasm diary. GABA-B weakness is the tradeoff.
Not indicated for rheumatic muscle ache. Sports 5 mg habits do not copy onto MS.
Rehab can write 80 mg a day and the job can still fail if legs buckle at 40. Mobility-first splits beat secret noon skips that start withdrawal. The 5 mg lock exists so those splits can be written in counted tablets, not guessed from a 20 mg bottle a neighbour donated.
Itchy arms after a Saturday miss on 60 mg a day can be early withdrawal. Monday pharmacy is late. Seek a bridge today. High fever, confusion, or a seizure after a gap is 112, not a wait-for-Monday plan. The withdrawal story is why this orbit refuses cold stops.
Week 22 pregnancy totals are not cold-stop projects. Neonatal withdrawal is labeled if the drug runs to delivery. Obstetrics and neurology write the taper together. Do not vanish the 5 mg tablets because a forum said third-trimester exposure is the only problem.
Intrathecal pump alarms at 23:00 are not ten-tablet oral nights. Oral math is not pump math. A silent oral rescue while the pump is empty is how overdoses and underdoses occupy the same weekend.
Forum 120 mg oral plans stay out. The labeled typical ceiling is 80 mg daily. Twenty-four 5 mg tablets from a leftover pile is not a titration. It is a ceiling breach with a withdrawal cliff attached.
Peer-pass wants last dose time and pump status on line one. Seizure or high fever after a gap is 112. Reviewed 21 August 2026. Sources stay DailyMed withdrawal and renal caution. Educational only. Ingrid does not taper by mail.
Renal impairment still deserves a read even when the star warning is withdrawal. People who treat 5 mg as candy because the tablet looks small skip that table. Confusion in an older adult after a climb is a hold, not another 5 mg.
Tizanidine swaps for hypotension still inherit this withdrawal rule. Do not cold-stop baclofen to simplify a CYP1A2 wall on Zanaflex. The spasm class is not one cliff.
Alcohol the same evening as a 20 mg slice of an 80 mg day is a stacked night. Harbour driving the next morning still counts. Confirm with the clinician if buckling already happened.
Icelandic holiday weekends empty 5 mg bottles quietly because people underestimate how many tablets 80 mg a day consumes. Call for a bridge. Do not invent every-other-day 40 mg from a leftover count.
GABA-B relief is also GABA-B weakness. Mobility goals belong on the same visit as spasm counts.
Not indicated for rheumatic muscle ache. Copying a sports 5 mg habit onto MS - or the reverse - scrambles expectations.
If benefits never appear after a fair trial, withdraw slowly. That sentence is on the label.
Methocarbamol is a short-spasm cousin, not a GABA-B twin. Do not treat them as interchangeable refills.
Renal excretion is why a 'normal' total becomes encephalopathy after an AKI week. Repeat eGFR after hospital vomiting.
Laugavegur peer-pass wants last dose time and pump status on the same slip. Ingrid does not taper by mail.
Sources stay DailyMed withdrawal, 80 mg ceiling, epilepsy and renal cautions. Forum 120 mg oral plans do not enter the chart.
Baclofen agonizes GABA-B. Flexor spasms and clonus can ease. Legs can also buckle. That tradeoff is why mobility goals belong on the same visit as spasm counts.
It is not indicated for rheumatic muscle ache. Copying a sports-medicine 5 mg habit onto MS spasticity - or the reverse - scrambles expectations.
Intrathecal pumps are a different labeled world with their own withdrawal disasters. Oral leftover tablets are not a travel patch without the pump team's blessing.
| Lane | Hook | Failure mode |
|---|---|---|
| Oral titration | Low, divided, toward 40-80 mg | Jumping to 20 mg TID night one |
| Oral ceiling | 80 mg/day typical | CKD patients using that as a target |
| Stop | Slow reduce | Saturday gap at high totals |
| Pump | Specialist only | Silent oral add-on |
If benefits never appear after a fair trial, withdraw slowly. That sentence is on the label.
Methocarbamol is not a GABA-B twin. Casual swaps inherit the wrong withdrawal story.
Repeat eGFR after hospital vomiting. A normal total becomes encephalopathy when clearance falls.
Peer-pass wants last dose time and pump status. Ingrid does not taper by mail.
Sources stay DailyMed withdrawal, 80 mg ceiling, epilepsy and renal cautions.
| Item | Note |
|---|---|
| If benefits never appear after a fair tr | chart |
| Methocarbamol is not a GABA-B twin. Casu | till |
Baclofen accumulates when clearance falls. Confusion that looks psychiatric can be drug. Elderly patients need lower ceilings than the 80 mg slogan.
Epilepsy is a caution - seizure control can worsen on baclofen, and withdrawal can seize on its own. Neurology should see the joined chart.
Neonatal withdrawal is labeled when oral baclofen runs through late pregnancy. Obstetric plans are written, not guessed.
Baclofen till habits
Withdrawal can include hallucinations, seizures, high fever, and rebound rigidity. Early signs can look like more spasm or itch.
The oral ceiling is 80 mg daily for typical adults. CKD and many older adults need a lower ceiling. Confusion can be accumulation.
The 5 mg lock is a low-step board. Jumping to 20 mg TID night one is how people decide the drug only weakens.
Intrathecal pumps are another world. Oral leftover 5 mg tablets are not a travel patch without the pump clinic.
Alcohol, opioids, and benzodiazepines add CNS depression. Light wine misses stairs.
Do not treat an empty Sunday bottle as a long weekend off. CKD and alcohol are the everyday stacks. Pumps are another chart.
Companions: taper, spasm, tizanidine if class switch is the cleaner path. Tapers need the clinician who wrote the last total.
Checked against the current label and reviewed by Dr. Ingrid Bergsson. See Lift, Chart, Peer-pass, Publish.
Baclofen withdrawal thread at Laugavegur, peer-passed by Dr. Ingrid Bergsson. Educational only. Seizure or rigidity after a gap: 112.
Arndis L., MS 20 mg three times daily - spasms better but legs buckle. Cut tonight?
The tradeoff is common. A secret cut after high totals can start withdrawal. Ask about a different split, PT, or a class look at tizanidine if mobility outranks spasm count. Document near-falls with times. The Caelum lock is the 5 mg tablet used for early steps - not a license to jump to 20 mg without a ladder. See the spasm orbit. Confirm with your clinician. Icelandic emergency: 112.
Valgerdur S., 40 Buckling at 40 mg a day, script says titrate to 80. I drive a harbour van.
The ceiling is not a driving clearance. Ask for a mobility-first plan. Do not secretly skip the noon slice. A skip can start withdrawal while the diary looks virtuous. Icelandic emergency: 112 if a seizure or high fever follows a gap.
Ida M., MS Legs buckle on 15 mg TID. Secretly skip the noon tablet.
Secret skips after a stable total can start withdrawal. Ask for a split change or class look. Document near-falls. Do not vanish the noon dose.
Jonas M., Kopavogur Wine at dinner plus 5 mg at 21:00. Light?
Alcohol plus baclofen stacks CNS depression. 'Light' is how people misjudge stairs. If you drink, skip extra night sedatives and skip driving.
Tomas E., itch Itchy arms and worse spasm after missing Saturday on 60 mg/day. Pharmacy Monday.
Those can be early withdrawal signs. Do not wait until Monday on a high prior total. Seek a bridge today.
Hannes Y., ran out Pharmacy closed Sunday. No baclofen since Saturday morning. I was on 80 mg/day.
A high-dose gap is a withdrawal emergency risk - hallucinations, seizures, rebound rigidity. Use on-call or urgent care for a bridge today. Do not borrow a neighbor's bottle. Read the taper trace after you have supply.
Stefan P., wine One glass with 5 mg at 21:00 after PT.
Alcohol plus baclofen is a stacked night even at the low-step lock. Skip the glass on a new-dose week. Sit before standing.
Olafur B., wine Celebratory wine after PT on a new 5 mg TID week.
Skip the glass on a new-dose week. Alcohol plus baclofen is a stacked night even at the low-step lock.
Lara H., pregnancy Twenty weeks, baclofen 10 mg TID for MS. Stop now?
Do not cold-stop a mid-pregnancy total. Neonatal withdrawal is labeled if baclofen runs to delivery. Obstetrics and neurology write the map. This desk will not invent a taper for you.
Helgi P., 22w Week 22, 10 mg three times daily, wants it gone before the third trimester.
Do not cold-stop. Ask obstetrics and neurology for a written taper. Neonatal withdrawal is labeled if the drug runs to delivery. The 5 mg tablets exist so a taper can be counted. Do not invent a weekend vanish.
Magnus T., Akureyri Seizure history - is baclofen off the table?
Baclofen can worsen seizure control in people with epilepsy. It is a caution, not an automatic ban. Neurology should own the chart if both sit together. Withdrawal seizures are a separate, uglier story after abrupt stop.
Kristjan D., pump Pump alarm at 23:00. I have oral 5 mg at home. Ten tablets tonight?
Oral math is not pump math. Call the pump team or emergency path your clinic wrote. Do not invent a ten-tablet oral night. A silent oral rescue while the reservoir is empty is how both overdose and withdrawal occupy one weekend.
Elin S., Hafnarfjordur CKD - same 80 mg max as my brother?
Baclofen accumulates when kidneys slow. Elderly and CKD patients get more encephalopathy on 'normal' totals. The 80 mg oral ceiling is for typical adults, not a CKD target. Ask for a lower ceiling.
Pia N., pregnancy Week 22, 10 mg TID, wants to stop before third trimester.
Do not cold-stop. Neonatal withdrawal is labeled if baclofen runs to delivery, and abrupt stop is also a risk. Obstetrics and neurology write the taper.
Nanna L., 120 Pain group said 120 mg if 80 fails. I have 5 mg tablets.
Eighty milligrams is the labeled typical oral ceiling. Do not build twenty-four 5 mg tablets from a forum. Ask the clinician who owns the 80 mg map. More tablets are not more legitimacy.
Gudrun F., 80 Rehab wrote 80 mg/day. I drive. Legs already buckle at 40.
The ceiling is not a driving clearance. Ask for a mobility-first split or a class look. Do not secretly skip tablets after a high total. Confirm with rehab. Icelandic emergency: 112.
Olaug K., itch Itchy arms and more spasm after missing Saturday. Wait until Monday?
Those can be early withdrawal signs after a gap. Do not wait until Monday on a high prior total. Seek a bridge today.
Jon P., pump alarm Pump alarm plus leftover oral 5 mg. Take six tablets?
Pump malfunctions are specialist emergencies. Inventing an oral bridge from 5 mg tablets without the pump team scrambles overdose and withdrawal math. Call the pump clinic or urgent care now.
Helga R., Reykjavik Intrathecal pump plus a few oral 5 mg tablets when I travel. OK?
Pump and oral are different worlds. Oral add-ons without the pump clinic's blessing scramble withdrawal and overdose math. Call the pump team before you invent a travel stack.
Anna S., CKD EGFR 28. Brother takes 80 mg/day and walks fine.
Your brother's clearance is not yours. Baclofen accumulates. Ask for a lower ceiling and a confusion watch. Do not chase 80 mg because spasm counts look similar.
Svana M., pump Pump alarm at 23:00. Ten leftover 5 mg tablets in the drawer.
Do not invent an oral bridge. Call the pump on-call or urgent care now. Oral math is not pump math.
Sara L., Selfoss Tizanidine instead because baclofen makes me weak. Stop baclofen today?
Class switch is reasonable. Cold stop is not. Taper first unless a clinician writes a rapid withdrawal for a serious adverse reaction. Compare the tizanidine orbit for the CYP1A2 wall you are walking into.
Niels V., 120 Forum says 120 mg oral if 80 fails. I have 5 mg tablets.
80 mg daily is the labeled oral ceiling for typical adults. Forum 120 mg plans do not enter this chart. Ask rehab why 80 failed before you build twenty-four 5 mg tablets. Icelandic emergency: 112.
Ragnar T., pump Pump clinic closed. Oral 5 mg x 10 to cover the night?
Do not invent an oral bridge from 5 mg without the pump team. Alarms and gaps are specialist emergencies. Urgent care or on-call now.
Desk note Minimum taper packet?
Current total mg/day, last dose time, written step-down dates, pump status, kidney labs, and sedative partners. Caelum educates. Ingrid does not taper by mail. Confirm with your clinician. Seizure or high fever after a gap: 112.